Cholesterol Efflux Pathway

Cholesterol Efflux PathwayMolecular Mechanisms of Cellular Cholesterol Efflux – jbc.org
Introduction. Because most cells in the periphery of the body do not express pathways for catabolizing cholesterol, efflux of cholesterol is critical for maintaining homeostasis.

ABCA1 – Wikipedia
With cholesterol as its substrate, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. While … Interactions between members of the apoliprotein family and ABCA1 activate multiple signalling pathways, including the JAK-STAT, PKA, …

Cholesterol Efflux Pathway Bioinformatics: Novus Biologicals
Learn more about the Cholesterol Efflux Pathway from related diseases, pathways, genes and PTMs with the Novus Bioinformatics Tool.

Involvement of cholesterol efflux pathway in the control …
The cholesterol efflux pathway reductions induced by cholesterol synthesis inhibition were not caused by a reduction of ABC transporter expression (mRNA or protein).

Cholesterol efflux pathways and other potential mechanisms …
You have free access to this content Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins

PDF An analysis of the role of a retroendocytosis pathway in …
An analysis of the role of a retroendocytosis pathway in ABCA1-mediated cholesterol efflux from macrophages … cholesterol efflux, especially if this small pool is rapidly turned over. To evaluate this possibility, we devised an

Reverse cholesterol transport and cholesterol efflux in …
Abstract. Reverse cholesterol transport (RCT) is a pathway by which accumulated cholesterol is transported from the vessel wall to the liver for excretion, thus preventing atherosclerosis.

Multidrug resistance: a role for cholesterol efflux pathways?
Fig. 2. Cellular cholesterol trafficking: a hypothetical role of cholesterol efflux pathways in drug export. Major cholesterol influx pathways (blue arrows) and efflux pathways (green arrows) are depicted schematically.

A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in …
A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis. Ajay Chawla 1, af, 2, William A … the sequential activation of the LXR-ABCA1 cholesterol efflux pathway by PPARγ in macrophages and the progression of atherosclerotic plaques in its absence in …

PDF Importance of Different Pathways of Cellular Cholesterol …
ATVB In Focus Role of ABCA1 in Cellular Cholesterol Efflux and Reverse Cholesterol Transport Series Editor: Alan R. Tall Importance of Different Pathways of Cellular

Multidrug resistance: a role for cholesterol efflux pathways?
Acquisition of MDR might thus be accompanied by upregulation of caveolin-dependent cholesterol efflux pathways, raising the possibility that these same pathways are utilized for delivering drugs from intracellular compartments to the plasma membrane …

Cholesterol Efflux Capacity, High-Density Lipoprotein …
Original Article from The New England Journal of Medicine — Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis. … Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins.

Regulation and mechanisms of macrophage cholesterol efflux
Regulation and mechanisms of macrophage cholesterol efflux Alan R. Tall, Philippe Costet, and Nan Wang … Three distinct pathways of cellular cholesterol efflux involving HDL and its apolipoproteins have been described. First, …

Cholesterol efflux pathways and other potential mechanisms …
How to Cite. Tall, A. R. (2008), Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins.

PDF Cholesterol efflux pathways regulate myelopoiesis: a …
Cholesterol efflux pathways regulate myelopoiesis: a potential link to altered macrophage function in atherosclerosis …

Importance of Different Pathways of Cellular Cholesterol …
Figure 1. Mechanisms of efflux of unesterified cholesterol from peripheral cells. A, Aqueous diffusion, an unmediated pathway that occurs in all cell types and is relatively inefficient.

Cholesterol efflux to apolipoprotein AI involves …
Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway. Yukihiro Takahashi and Jonathan D. Smith * The Rockefeller University … The second pathway for cholesterol efflux, …

Lipoprotein Signaling & Cholesterol Metabolism PCR Array
Lipoprotein Signaling & Cholesterol Metabolism PCR Array. … Human Lipoprotein Signaling & Cholesterol Metabolism PCR Array: … Cholesterol Efflux: ABCA1, ABCG1, APOA1, APOA4, APOC3, APOE.

Cholesterol Efflux Pathways Regulate Myelopoiesis: A …
Cholesterol Efflux Pathways Link HSPC Proliferation, Monocyte Production, … (2014) Cholesterol efflux pathways regulate myelopoiesis: a potential link to altered macrophage function in atherosclerosis. Front. Immunol. 5:490. doi: 10.3389/fimmu.2014.00490.

Small HDL Promotes Cholesterol Efflux by the ABCA1 Pathway …
A key feature of the current model is that discoidal and more mature forms of HDL do not promote sterol efflux by the ABCA1 pathway (Figure A). The model also implies that increased LCAT activity should promote sterol efflux from macrophages.

PDF Cholesterol Efflux Pathways in Dendritic Cells Suppress …
Cholesterol Efflux Pathways in Dendritic Cells Suppress Autoimmune Responses . Marit Westerterp, Columbia Univ, New York, NY; Emmanuel L Gautier, Washington Univ Medical Sch,

Multidrug resistance: a role for cholesterol efflux pathways?
Multidrug resistance: a role for cholesterol efflux pathways? Mordechai Liscovitch. x. Mordechai Liscovitch. Search for articles by this author Affiliations. Dept of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.

Activation of the TLR4 signaling pathway and abnormal …
Activation of the TLR4 signaling pathway and abnormal cholesterol efflux lead to emphysema in ApoE-deficient mice

Macrophage Reverse Cholesterol Transport – Circulation
Cholesterol Efflux From Nonmacrophage Tissues: Critical for Maintaining Normal HDL Biosynthesis and Metabolism. A discussion of RCT should begin with a discussion of the recent developments in our understanding of the biosynthesis of HDL . It has been known for quite some …

Importance of Different Pathways of Cellular Cholesterol …
Efflux of cholesterol is accelerated when scavenger receptor … The relative importance of the SR-BI and ABCA1 efflux pathways in preventing the development of atherosclerotic plaque is not known but will depend on the expression levels of the two proteins and on the …

Small HDL Promotes Cholesterol Efflux by the ABCA1 Pathway …
Small HDL Promotes Cholesterol Efflux by the ABCA1 Pathway in Macrophages Implications for Therapies Targeted to HDL

PDF Cholesterol efflux to apolipoprotein AI involves …
Cholesterol efflux to apolipoprotein AI involves endocytosis and … dependent pathway for cholesterol efflux to apolipoproteins involving receptor-mediated endocytosis in coated pits fol-lowed by the resecretion of a nascent lipoprotein particles.

Cholesterol Serum Influx/Efflux – diff
Cholesterol efflux from the cell. The cholesterol efflux from the cell is mediated by a carrier called ABCA1 belonging to the family of ABC transporter. … Regulation of cholesterol metabolism by Nuclear Factors. Sterol response element binding protein …

Cellular SR-BI and ABCA1-mediated cholesterol efflux are …
Abstract. We evaluated the impact of gender differences in both the quantitative and qualitative features of HDL subspecies on cellular free cholesterol efflux through the scavenger receptor class B type I (SR-BI), ABCA1, and ABCG1 pathways.

Pathway of cholesterol efflux from human hepatoma cells …
Read "Pathway of cholesterol efflux from human hepatoma cells" on DeepDyve – Instant access to the journals you need!

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